Polyuria: The excessive passage of urine (at least 2.5 liters per day for an adult) resulting in profuse urination and urinary frequency (the need to urinate frequently).
Polyuria is a classic sign of diabetes mellitus that is under poor control or is not yet under treatment. Polyuria occurs in some other conditions such as: Nephrogenic diabetes insipidus -- a genetic disease Polycystic kidney disease -- another genetic disease Sickle cell disease Pyelonephritis -- infection of kidneys Amyloidosis -- deposits of a substance called amyloid in the kidney Sjogren syndrome, and Myeloma.
Certain drugs such as the mood stabilizer lithium and the antibiotic Declomycin (demeclocycline) can also lead to polyuria.
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