BP1

BP1: Beta protein 1, a member of the homeobox gene family important to early development of the fetus. (Specifically, BP1 belongs to the DLX homeobox family and is an isoform of the DLX4 gene.) BP1 acts as a transcription factor that turns other genes on and off. It regulates the beta globin gene, from whence comes its name. BP1 is overexpressed in a large proportion of cases of acute myeloid leukemia (AML) and breast cancer.