Amyotrophic lateral sclerosis 1

Amyotrophic lateral sclerosis 1: ALS1. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner and caused by mutation in the superoxide dismutase-1 gene (SOD1) on chromosome 21q22.1. About 15 to 20% of familial ALS is type 1 (ALS1). Sporadic cases of ALS are sometimes due to new mutation in the SOD1 gene.

Common Misspellings: amyotrophic lateral sklerosis 1, amyotrophic lateral sclorosis 1, amyotrophic lateral schlerosis 1, amyotrophic lateral scleroses 1